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Evidence & Medical Affairs

We design and deliver integrated evidence strategies that bridge clinical development, medical affairs, and market access — creating measurable value across the product lifecycle.

Evidence & Medical Affairs

We design and deliver integrated evidence strategies that bridge clinical development, medical affairs, and market access — creating measurable value across the product lifecycle.

Explore Our Medical Affairs Work
Creative Marketing & Medical Communications

We transform complex data and evidence into clear, compelling narratives — helping organizations engage clinicians, patients, and stakeholders with authenticity and impact.

Creative Marketing & Medical Communications

We transform complex data and evidence into clear, compelling narratives — helping organizations engage clinicians, patients, and stakeholders with authenticity and impact.

Discover Our Communications Expertise
Government Affairs & Policy Innovation

We help organizations translate evidence and advocacy into equitable health policy — building strategies that expand access, sustainability, and inclusion at every level.

Government Affairs & Policy Innovation

We help organizations translate evidence and advocacy into equitable health policy — building strategies that expand access, sustainability, and inclusion at every level.

Learn How We Advance Health Equity
Patient Advocacy & Partnership

We work with advocacy groups and health organizations to amplify patient voices, foster trust, and shape more human-centered systems of care.

Patient Advocacy & Partnership

We work with advocacy groups and health organizations to amplify patient voices, foster trust, and shape more human-centered systems of care.

See Our Advocacy Collaborations
AI-Enabled Platform & Intelligence

We integrate AI and analytics to unify data, evidence, and insight — helping clients uncover patterns, accelerate decision-making, and future-proof their strategies.

AI-Enabled Platform & Intelligence

We integrate AI and analytics to unify data, evidence, and insight — helping clients uncover patterns, accelerate decision-making, and future-proof their strategies.

Learn About Our AI Platform
Global & Public Health

We develop global and public health strategies that fortify systems, advance equity, and spark innovation to improve outcomes across LMICs and beyond.

Global & Public Health

We develop global and public health strategies that fortify systems, advance equity, and spark innovation to improve outcomes across LMICs and beyond.

See Our Global Health Work
Emergency Response
Vaccine Strategy
Health Equity

🦠

White House Emergency Response
National Mpox Response: From Crisis to 99% Case Reduction

How a syndemic strategy, innovative vaccine delivery, and equity-centered communication transformed the national mpox response into a public health success story.

99%

Case Reduction

1.2M+

Vaccines Administered

6 mo

Peak to Control

Read Case Study
Value Frameworks
Market Access
Oncology

📈

Value Framework Strategy
Optimizing Market Positioning Through Value Frameworks

Strategic analysis across NCCN, ASCO, and ICER methodologies to strengthen guideline positioning, influence payer decisions, and accelerate coverage for an oncology drug's extended indication.

Cat 2A

NCCN Recommendation

3

Frameworks Analyzed

Coverage Accelerated

Read Case Study
Market Analysis
Neurology
Competitive Intelligence

🧠

Neurology Market Intelligence
Comprehensive Neurology Market Landscape Assessment

Developing deep market intelligence and competitive landscape analysis to inform strategic decisions for neurology pipeline assets, identifying opportunities and risks across a complex therapeutic area.

Deep

Market Analysis

Multi

Indication Coverage

Pipeline

Assessment

Read Case Study
Health Equity
HIV Prevention
Urban Health

🏙️

Urban Health Innovation
Transforming Urban HIV Prevention Strategy in New York City

Leading the NYC Department of Health's HIV/AIDS prevention and control programs, managing a portfolio of over $250 million across HIV, TB, STD, immunization, and laboratory programs.

$250M

Budget Managed

Multi

Program Portfolio

NYC

Scale

Read Case Study
HEOR
Value-Based Care
Oncology

💹

Value-Based Care Strategy
Enhancing Market Access for Oncology Drug Under OCM

A data-driven strategy leveraging real-world evidence, actuarial modeling, and HEOR analytics to optimize drug positioning within the Oncology Care Model's episode-based payment structure.

6mo

Episode Analysis

RWE

Data-Driven

Multi

Scenario Modeling

Read Case Study
Global Health
HIV/AIDS
PEPFAR

🎗️

Global HIV Response
Leading PEPFAR Implementation in Nigeria and Zambia

Providing leadership and oversight of CDC's HIV programs as part of the President's Emergency Plan for AIDS Relief, serving as key health advisor to US Ambassadors on critical public health matters.

2

Countries Led

PEPFAR

Program Scale

Multi

Disease Portfolio

Read Case Study
Launch Strategy
Market Access
Commercial

🚀

Launch Excellence
Comprehensive Pharmaceutical Launch Strategy and Execution

Developing and executing integrated launch strategies that align clinical evidence, market access, and commercial positioning to maximize therapeutic impact and commercial success.

Cross

Functional Integration

Market

Access Aligned

Field

Team Enabled

Read Case Study
Clinical Research
PRO Innovation
Mental Health

🧠

PRO-Biomarker Integration
Leveraging Patient-Reported Outcomes for PTSD Treatment Innovation

A Phase IIa RCT demonstrating how validated PRO measures combined with biomarkers can enhance clinical validation, regulatory credibility, and patient-centric drug development in mental health therapeutics.

50%

Treatment Gap Addressed

6

PRO Instruments

hs-CRP

Biomarker Correlation

Read Case Study
Corporate Responsibility
Philanthropy
Health Equity

💝

Strategic Philanthropy
Building Strategic Philanthropy Programs for Health Impact

Developing and leading corporate philanthropy and social business innovation programs that align business objectives with meaningful health equity outcomes, creating sustainable models for corporate social impact.

Global

Reach

Equity

Centered

Business

Aligned

Read Case Study
HTA Strategy
PRO/QOL
Market Access

📊

HTA Evidence Strategy
Strategic PRO/QOL Evidence for Successful UK HTA Submission

Developing a comprehensive patient-reported outcomes and quality of life evidence strategy to support a successful NICE submission for a specialty therapeutic.

NICE

HTA Submission

PRO

Evidence Package

QOL

Data Strategy

Read Case Study
Launch Excellence
Market Access
Cell & Gene Therapy

🧬

Cell Therapy Launch Excellence
Accelerated Access Toolkit for First-in-Class Cell Therapy

Delivering a comprehensive HCP billing and access toolkit under accelerated approval timelines—empowering treatment centers to operationalize a pioneering oncology cell therapy from day one.

5

Toolkit Components

On Time

Delivery

Under

Budget

Read Case Study
Operations
Cell & Gene Therapy
KOL Engagement

🧬

CGT Workflow Optimization
Optimizing Clinical Workflow for Complex Cell & Gene Therapy

An advisory board-driven initiative creating practical workflow tools to streamline the complex patient onboarding journey—from financial clearance through infusion—for cell and gene therapy centers.

Multi

Step Onboarding

AdBoard

Expert-Driven

Unbranded

Practical Tool

Read Case Study
Emergency Response
Vaccine Strategy
Health Equity

🦠

White House Emergency Response
COVID-19 Vaccine Commercialization: From Crisis to Seamless Transition

How a syndemic strategy, innovative vaccine delivery, and equity-centered communication transformed the national COVID-19 response into a public health success story.

99%

Case Reduction

1.2M+

Vaccines Administered

6 mo

Peak to Control

Read Case Study
Emergency Response
Global Health
CDC

🌍

Global Emergency Response
Coordinating the West African Ebola Emergency Response

Leading CDC's agency-wide coordination during the largest Ebola outbreak in history, managing interagency collaboration with US government counterparts and international partners across three affected countries.

3

Countries Affected

Multi

Agency Coordination

Global

Partner Network

Read Case Study
Health Systems
Fragile States
Capacity Building

🏥

Health Systems Strengthening
Health Systems Strengthening in Guinea-Bissau

Building sustainable health infrastructure and local capacity in one of the world's most fragile states, demonstrating that meaningful progress is possible even in the most challenging contexts.

Fragile

State Context

Multi

Sector Approach

Local

Capacity Focus

Read Case Study
Patient Access
Partnership
HIV

💊

Patient Access Innovation
Ensuring HIV Medication Access During COVID-19 Lockdowns

An innovative multi-partner program combining exercise, medication adherence support, and transportation to serve aging individuals with HIV when clinical trial access was disrupted by pandemic restrictions.

4

Partner Organizations

Full

Program Funding

Regional

Expansion Achieved

Read Case Study
Implementation Science
Capacity Building
Migrant Health

🎓

Implementation Science Training
Building Implementation Science Capacity for Migrant Health in MENA

A specialized training initiative enhancing the capacity of public health officials to translate research into practical interventions—establishing a scalable model now replicated across Columbia Global Centers.

5

Day Workshop

3

IS Frameworks

3

Partner Institutions

Read Case Study
Global Health
Migrant Health
MENA Region

🌍

Migrant Health Research
Advancing Migrant and Refugee Health in the MENA Region

Developing evidence-based approaches to address the health needs of displaced populations across the Middle East and North Africa, where millions of refugees and migrants face barriers to healthcare access.

MENA

Regional Focus

Multi

Country Approach

Evidence

Based Strategy

Read Case Study
Emergency Response
Vaccine Strategy
Health Equity

🦠

White House Emergency Response
1 National Mpox Response: From Crisis to 99% Case Reduction

How a syndemic strategy, innovative vaccine delivery, and equity-centered communication transformed the national mpox response into a public health success story.

99%

Case Reduction

1.2M+

Vaccines Administered

6 mo

Peak to Control

Read Case Study
our work

Impact Stories

Real-world examples of how our team has translated evidence into outcomes — from national emergency responses to global health initiatives.

Evidence & Medical Affairs

From Data to Decisions

Heading 6

We design and deliver integrated evidence strategies that bridge clinical development, medical affairs, and market access — creating measurable value across the product lifecycle.

Our Approach
  • Scientific & Clinical Strategy Development

  • HEOR/Real-World Evidence Insights

  • Stakeholder Engagement & Thought-Leader Strategy

  • Evidence Generation & Real-World Data Strategy

  • Regulatory & Compliance Alignment

  • Health Policy, Access, and Systems-Level Insight

  • Data Interpretation, Publications, & Scientific Exchange

Creative Marketing & Medical Communications

Where Science Meets Story

Heading 6

We transform complex data and evidence into clear, compelling narratives — helping organizations engage clinicians, patients, and stakeholders with authenticity and impact.

Our Approach
  • Brand & Positioning Strategy

  • Integrated Campaign Development (HCP, Payer, Patient)

  • Scientific & Medical Communications Excellence

  • Content Development & Storytelling

  • Omnichannel & Digital Engagement Strategy

  • Patient & Community-Facing Communications

  • Reputation, Issues Management & Thought Leadership

Government Affairs & Policy Innovation

Designing Systems That Include Everyone

Heading 6

We help organizations translate evidence and advocacy into equitable health policy — building strategies that expand access, sustainability, and inclusion at every level.

Our Approach
  • Federal Policy Navigation

  • Regulatory & Legislative Strategy

  • Stakeholder & Interagency Engagement

  • Public Health Systems Insight

  • Policy Design & Innovation

  • Advocacy & Coalition Development

  • Risk, Compliance & Scenario Planning

Patient Advocacy & Partnership

Centering Lived Experience

Heading 6

We work with advocacy groups and health organizations to amplify patient voices, foster trust, and shape more human-centered systems of care.

Our Approach
  • Advocacy Ecosystem Mapping:

  • Patient-Centric Strategy Development:

  • Community Partnership Models

  • Co-Creation & Insight Integration

  • Access, Equity & Public Health Alignment

  • Advocacy Communications & Engagement

AI-Enabled Platform & Intelligence

Powering Strategy with Intelligent Insights

Heading 6

We integrate AI and analytics to unify data, evidence, and insight — helping clients uncover patterns, accelerate decision-making, and future-proof their strategies.

Our Approach
  • Data harmonization & evidence mapping

  • Predictive and strategic analytics

  • AI-driven insight generation

Global & Public Health

Strengthening Systems, Advancing Equity

Heading 6

We develop global and public health strategies that fortify systems, advance equity, and spark innovation to improve outcomes across LMICs and beyond.

Our Approach
  • Multilateral & Government Engagement

  • Program Design & Implementation

  • Health Systems Strengthening

  • Global Regulatory & Access Strategy

  • Crisis Response & Preparedness

  • Equity & Community Partnership Models

Evidence & Medical Affairs
Creative Marketing & Medical Communications
Government Affairs & Policy Innovation
Patient Advocacy & Partnership
AI-Enabled Platform & Intelligence
Global & Public Health

Ready to Transform Evidence into Impact?

Let's discuss how Metli can help your organization move from data to decisions that matter.

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